Single-nucleotide polymorphisms (SNPs) may cause a disease or predispose an individual to a disease. High-throughput screening of known SNPs in a large set of samples offers opportunities to study the impact of such variants on for example disease predisposition. At Biogazelle qPCR is applied for high-throughput targeted SNP genotyping in DNA.
Related topics: custom primer design, sample preparation, qPCR, clinical trials, qbase+, quality, why Biogazelle
"High quality service, very good communication with laboratory staff."
post-doctoral researcher at Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
While SNP genotyping on a genome-scale is currently dominated by microarrays and to a lesser extent massively parallel sequencing, detection of a targeted selection of SNPs is mainly done by qPCR. qPCR using hydrolysis probes is the most commonly used PCR method for genotyping. Biogazelle offers medium and large-scale genotyping studies using TaqMan SNP Genotyping Assays.
Technologiepark 82
B-9052 Zwijnaarde
Belgium
email: info@biogazelle.com
phone: +32 9 245 96 43
fax: +32 9 251 56 56