Gene expression analysis services

Gene-expression analysis is fundamental in many fields of biological research and provides a better understanding of dynamic changes in a cell, tissue or organism. Understanding patterns of expressed coding and non-coding genes gives insight into complex regulatory networks and leads to the identification of genes relevant in biological processes, implicated in specific diseases or disease states. This information opens new opportunities for improving diagnosis and the identification of new biomarkers.

At Biogazelle RNA sequencing technology is used to study transcriptome wide gene expression, while qPCR is applied for gene expression analysis of specific genes of interest.

With more than 15 years of expertise in gene expression analysis, supported by more than 20,000 citations of peer reviewed articles and a pioneering role in the non-coding RNA field, Biogazelle is your preferred partner for all your gene expression studies.

Biogazelle has set internationally recognized standards in the field of gene expression analysis: SEQC, miRQC, MIQE, geNorm, qbase+, RDML

Transcriptome wide profiling with RNA sequencing

RNA sequencing enables unbiased, specific and sensitive measurement of expressed genes. Transcriptome wide gene expression analysis allows studying a disease mechanism, understanding a drug’s mode of action or developing a multi-gene biomarker signature, among other applications. Biogazelle offers a complete solution for all RNA sequencing projects on human, mouse and rat samples for a wide variety of RNA biotypes (mRNA, microRNA and lncRNA) and sample type (including liquid biopsies, whole blood and fixed tissues amongst other).

In addition to our whole transcriptome RNA sequencing workflows, we also offer a comprehensive analysis of the cancer transcriptome using a pan-cancer panel comprised of 1385 genes.

Let us help you to select the right RNA sequencing workflow for your sample type and application.

Targeted gene expression analysis with RT-qPCR

For targeted gene expression studies for specific mRNA, microRNA or lncRNA genes or gene panels, off-the-shelf assays for almost all genes are available. In addition, a large number of gene expression panels (mRNA, microRNA and lncRNA) for a broad range of pathways and disease states are offered. For genes where no off-the-shelf assay is available, custom assays are developed using our proprietary and ISO17025 accredited primerXL design engine. Find out whether we have the right RT-qPCR assay or gene panel for your project.

Benefits of our gene expression analysis solutions

Available for any kind of sample: cells, tissues, FFPE, whole blood, PBMCs, plasma, serum, urine, CSF, stool, etc.
Applicable to human, mouse, rat and 10 additional common model organisms
Suitable for messenger RNA, microRNA and long non-coding RNA
Include sample preparation: RNA extraction and quality control
Genome-wide profiling using (small) RNA sequencing technology
Targeted gene expression analysis for specific genes or gene panels with RT-qPCR using validated qPCR workflows
We select a suitable normalization strategy, including selection of reference genes
Data processing using validated software: qbase+ for qPCR and Cobra for RNA sequencing
Performed in an ISO17025 accredited and GCLP-compliant environment

Gene expression analysis

Transcriptome wide profiling with RNA sequencing

Targeted gene expression analysis with RT-qPCR

Benefits of our gene expression analysis solutions

Subscribe to email updates

Biogazelle

Menu

Contact us