Analytical characterization of a multiplex panel measuring 45 cytokines by proximity extension assay in plasma from subjects with NSCLC

April 17, 2023

Anne Jang, Daniel Feingold, Mark Watson, Gwenaël Pottiez, Rudolf Guilbaud, and Nicholas Dupuis

Analytical characterization of a multiplex panel measuring 45 cytokines by proximity extension assay in plasma from subjects with NSCLC
AACR 2023

Multiplex panel characterization

• Broad spectrum cytokine profiling increasingly utilized to map out pharmacodynamic effects for investigational new drugs
• The 45-cytokine panel evaluated is highly sensitive
• The assays are precise across runs and operators
• Additional pre-analytical characterization may be required when analyzing serum samples